Friday, May 27, 2022
New Bone Reconstruction Technology with sound waves
Source: RMIT University (pub:Small (DOI: 10.1002 / smll.202106823))

By using high-frequency sound waves directed at human stem cells, scientists were able to convert them into bone cells much faster than previously possible. The new method has great potential and could help patients to faster regenerate bones.

Bone reconstruction using sound waves

Stem cells have the incredible ability to transform into any other type of cell. Some organisms use this power to regenerate different parts of the body, which is why stem cells are the subject of much research. Scientists want to learn their secrets in order to use their regenerative abilities in humans. However, this requires the ability to manipulate stem cells. Australian scientists from RMIT University have made great achievements in this field.

Tissue engineering is an emerging field that aims to rebuild, regenerate or modify biological tissues, and even entire organs, by using the body's natural ability to heal itself. RMIT researchers focused on regenerating bone tissue in patients who lost it due to cancer or degenerative diseases. A key challenge in bone reconstruction is the effective conversion of large numbers of stem cells into bone cells, which will continue to grow after implantation in the target area.

Until now, complex and expensive equipment has been used in the experimental process of converting adult stem cells into bone cells. In addition, there were constant problems with the mass production of such cells, which made the widespread clinical use unrealistic. Several clinical trials have attempted to rebuild bone that have largely used stem cells from the patient's bone marrow, which is a very painful procedure.

New research, published in the journal Small (DOI: 10.1002 / smll.202106823), presents an innovative approach to the regeneration of damaged bones. Using high-frequency sound waves, scientists were able to transform stem cells into bone tissue cells. The new therapy consisted in 10-minute stimulation of stem cells with sound waves. The therapy only required five treatments to get the stem cells to differentiate into osteoblasts, or bone-forming cells.

 

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New Bone Reconstruction Technology with sound waves
Source: RMIT University (pub:Small (DOI: 10.1002 / smll.202106823))

By using high-frequency sound waves directed at human stem cells, scientists were able to convert them into bone cells much faster than previously possible. The new method has great potential and could help patients to faster regenerate bones.

Bone reconstruction using sound waves

Stem cells have the incredible ability to transform into any other type of cell. Some organisms use this power to regenerate different parts of the body, which is why stem cells are the subject of much research. Scientists want to learn their secrets in order to use their regenerative abilities in humans. However, this requires the ability to manipulate stem cells. Australian scientists from RMIT University have made great achievements in this field.

Tissue engineering is an emerging field that aims to rebuild, regenerate or modify biological tissues, and even entire organs, by using the body's natural ability to heal itself. RMIT researchers focused on regenerating bone tissue in patients who lost it due to cancer or degenerative diseases. A key challenge in bone reconstruction is the effective conversion of large numbers of stem cells into bone cells, which will continue to grow after implantation in the target area.

Until now, complex and expensive equipment has been used in the experimental process of converting adult stem cells into bone cells. In addition, there were constant problems with the mass production of such cells, which made the widespread clinical use unrealistic. Several clinical trials have attempted to rebuild bone that have largely used stem cells from the patient's bone marrow, which is a very painful procedure.

New research, published in the journal Small (DOI: 10.1002 / smll.202106823), presents an innovative approach to the regeneration of damaged bones. Using high-frequency sound waves, scientists were able to transform stem cells into bone tissue cells. The new therapy consisted in 10-minute stimulation of stem cells with sound waves. The therapy only required five treatments to get the stem cells to differentiate into osteoblasts, or bone-forming cells.